AI AgentTools & ProtocolsUpdated 2026.04.28

OpenAI Assistants API

Also known asAssistants APIOpenAI Agents SDK

In one line

OpenAI's Assistants API is the company's hosted toolkit for building agents — bundling tool use, files, memory and the execution loop into one managed service.

Going deeper

The Assistants API is OpenAI exposing the agent capabilities behind ChatGPT to outside developers. Tool use, file search, code interpreter and thread-based memory come bundled, so you can ship an agent without hand-rolling the ReAct loop.

For marketers it is the fastest path to a working prototype inside the OpenAI ecosystem. The trade-off is vendor lock-in, which is why more teams are pairing it with vendor-neutral standards like MCP.

Since 2025 OpenAI has been splitting the API into separate products — Agents SDK, Realtime API and friends. The naming moves often, so check the latest docs before you commit to an interface.

Related terms

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